Muscle Performance

Journal of Applied Physiology

“[A]t least two main additional factors could play a role in the observed changes in muscle performance: increases in capillary contacts per fiber, and oxidative capacity. This is the first study to characterize the effect of IPC treatment on these two variables in a model of peripheral arterial insufficiency.”

“We have shown for the first time that 2 wk of daily applications of intermittent pneumatic leg compressions produces significant improvements in exercise tolerance in a preclinical model of peripheral arterial insufficiency. This functional benefit appears to stem, at least in part, from improved blood flow to collateral-dependent tissues. These novel findings encourage additional efforts to determine the mechanistic basis behind the functional improvements associated with this novel therapeutic strategy.”

Roseguini, B. T., Arce-Esquivel, A. A., Newcomer, S. C., Yang, H. T., Terjung, R., & Laughlin, M. H. (2012). Intermittent pneumatic leg compressions enhance muscle performance and blood flow in a model of peripheral arterial insufficiency. Journal Of Applied Physiology, 112(5), 1556-1563